Effect Of Mangrove Leaf Extract Dosage Rhizophora Mucronata Lmk. On The Viability Of Hela Cells

This study aims to determine the IC50 value of mangrove leaf extract type Rhizophora mucronata Lmk. against viability Hela cells. The samples extracted with three types solvents were previously conducted preliminary research on phytochemical compounds and their toxicity values Meted Brine Shrimp Letality Test (BSLT). In test, highest level was obtained in ethanol a 166.72± 7.72 ppm, then sample continued for cytotoxicity test using MTT method. dosage variants used this 62.5 ppm; 125 250 500 1000 ppm. variation shows an effect cells, namely decrease percentage living cells along addition dose Lmk leaves. which is given. And from 63.67 µg / mL toxic category